Trimethylsilyl Acetylene (intermediate for asymmetric synthesis)

• Type: Pharmaceutical Intermediates
• Appearance: Liquid
• Quality: Industrial
• Colour: Colorless
• Transport Package: 200kg/Drum
• Specification: 98%
• Model NO.: TMSA
• Trademark: DEBORN
• Origin: China

Product Description

Name: Trimethylsilylacetylene

Molecular Formula: C5H10Si ((CH3)3SiC≡ CH

Molecular Weight: 98.21

CAS Registry Number: 1066-54-2
Appearance: Colorless transparent liquid
Content: ≥ 98 %
Boiling point: 50~52 C/760mmHg

Silican-protected group

Trimethylsilylacetylene is a silican-protected group, also known as trimethylethynylsilane, trimethylethynyl silicon and ethynyltrimethylsilane. It is a colorless transparent liquid at room temperature. It could be used to synthesize parazole by the addition of 1,3-bipolar ring of acetylene diazide. It is also the substrate of nickel catalyzed reaction and benzonitrile coupling reaction.

Application

An important spice and pharmaceutical intermediate
Silica reagent
Properties: Flammable, susceptible to oxidation and color darkening in open air